• Photosensitizers used in current photodynamic therapy can only release reactive oxygen species (ROS) which limits the application.
• On the other hand, upconverting nanoparticles (UCNPs) which can be applied on different drugs require multiphoton processes leading to low quantum yield, which limits its photolysis performance.
• There is a need to explore a new strategy which could achieve photolysis with high efficiency and long-wavelength light excitation.

• HKU researcher have proven that drug release can be triggered under long wavelength light excitation in tumor site.
• Micelles can enhance the tumor cell uptake of the drug to achieve higher therapeutic performance.
• On-demand drug release
• Long wavelength light excitation leading to deep tissue penetration
• Applicable to different drugs leading to broad applications

• Drug delivery system for photodynamic therapy, such as skin diseases or ophthalmological diseases

Patents

• PCT application

IP Status

• Patent application submitted